Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma

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Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma

Numb chin syndrome is a rare sensory neuropathy of the mental nerve characterized by numbness, hypoesthesia, paraesthesia, and very rarely pain. Dental causes, especially iatrogenic ones, maxillofacial trauma, or malignant neoplasm are etiologic factors for this rare syndrome. Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, ...

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Numb Chin Syndrome with Concomitant Painful Ophthalmoplegia Leading to a Diagnosis of Diffuse Large B Cell Lymphoma

Painful ophthalmoplegia (PO) and concomitant numb chin syndrome (NCS) is a very rare event. There are a few reports in the literature about PO and concomitant NCS that have preceded the diagnosis of a malignancy. In this report, we describe a patient with diffuse large B cell lymphoma who presented with PO and concomitant NCS as the initial symptom of the disease.

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The numb chin syndrome (NCS) is a rare neurological condition which origins in the absence of a dental cause and is most often associated with malignancy [1–5]. Patients develop orofacial paraesthesia typically localized to the chin and lower lip. We present a series of four female patients (mean age = 66.2 years) who had been diagnosed with breast cancer and were complaining of orofacial numbn...

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ژورنال

عنوان ژورنال: Case Reports in Dentistry

سال: 2014

ISSN: 2090-6447,2090-6455

DOI: 10.1155/2014/413162